Antihypertensive drug chlorotoluene thiazide, also known as diazine, rapidine, antihypertensive drug, is a kind of antihypertensive drug, with the basic structure of thiazide diuretic drugs, but no diuretic effect. Direct dilation of arterioles has no obvious effect on veins. It is possible that by activating ATP-sensitive potassium channels, arterial smooth muscle cells are hyperpolarized, smooth muscle relaxation is generated, peripheral vascular resistance is reduced, and blood pressure is decreased. While lowering blood pressure, the heart rate increases and cardiac output does not decrease. However, blood pressure drop reflexes Chemicalbook arouses sympathetic nerve, leading to tachycardia, myocardial contractile force enhancement, cardiac output increase, partially offsetting the antihypertensive effect of drugs, and can aggravate the heart burden, induce or aggravate angina pectoris, but also increase renin secretion, secondary increase aldosterone secretion, resulting in water and sodium retention. It can be corrected with b receptor blockers and diuretics. It is suitable for first aid in hypertensive crisis, and also for hyperglycemia, idiopathic hypoglycemia in children, and severe hypoglycemia caused by islet cell tumor.